SCHEMBL9547715

SCHEMBL9547715

S=C=Nc1ccc(CCc2ccc(N=C=S)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 2/20 1.00
MIF P14174 8/20 0.54
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HSD17B10 Q99714 1/20 0.44
CYP3A4 P08684 2/20 0.43
TSHR P16473 1/20 0.43
TRPA1 O75762 1/20 0.40
CYP2E1 P05181 1/20 0.40
CYP2A6 P11509 1/20 0.40
HIF1A Q16665 1/20 0.40
CYP2A13 Q16696 1/20 0.40
EPAS1 Q99814 1/20 0.40
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
ALOX12 P18054 1/20 0.36
CHRM1 P11229 1/20 0.36
GFER P55789 1/20 0.36
ESR1 P03372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1853024 1.00 P2RY6 (1.00) P2RY6MIFCA1CA2HSD17B10
SCHEMBL347652 0.89 P2RY6 (0.79) P2RY6MIFCA1CA2HSD17B10
SCHEMBL27467439 0.87 P2RY6 (0.76) P2RY6MIFCA1CA2HSD17B10
SCHEMBL5186242 0.87 P2RY6 (0.76) P2RY6MIFCA1CA2HSD17B10
SCHEMBL8503279 0.87 P2RY6 (0.76) P2RY6MIFCA1CA2HSD17B10
SCHEMBL3880561 0.87 P2RY6 (0.76) P2RY6MIFCA1CA2CYP2A6
SCHEMBL6417472 0.87 P2RY6 (0.76) P2RY6MIFCA1CA2HSD17B10
SCHEMBL1193625 0.85 P2RY6 (0.74) P2RY6MIFCA1CA2HSD17B10
SCHEMBL9547731 0.85 P2RY6 (0.74) P2RY6MIFCA1CA2HSD17B10
SCHEMBL9840376 0.85 P2RY6 (0.73) P2RY6MIFCA1CA2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0378895-B1 A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-14 EP disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed