Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27577519 | 0.83 | MAOB (0.50) | MAOBMRGPRX4MAOAFFAR1LMNA | |
| SCHEMBL28785862 | 0.82 | MRGPRX4 (0.48) | MAOBMRGPRX4L3MBTL1 | |
| SCHEMBL15472489 | 0.81 | ALOX5 (0.56) | MAOBMRGPRX4MAOAALOX5LMNA | |
| SCHEMBL28123955 | 0.79 | MAOB (0.49) | MAOBMRGPRX4MAOAFFAR1PPARD | |
| SCHEMBL5045302 | 0.79 | MRGPRX4 (0.48) | MAOBMRGPRX4MAOAFFAR1PPARD | |
| SCHEMBL9127224 | 0.79 | ALOX5 (0.54) | MAOBMRGPRX4ALOX5 | |
| SCHEMBL27577521 | 0.78 | MAOB (0.47) | MAOBMRGPRX4MAOAALOX5 | |
| SCHEMBL28343888 | 0.78 | ALOX5 (0.47) | MAOBMRGPRX4FFAR1PPARDALOX5 | |
| SCHEMBL28343890 | 0.78 | ALOX5 (0.47) | MAOBMRGPRX4FFAR1PPARDALOX5 | |
| SCHEMBL27821048 | 0.78 | KMT2A (0.46) | MAOBALOX5LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288297-B1 | OPTICALLY ACTIVE BENZENE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4985590-A | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |