Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.91 |
| ▸ | MAOA | P21397 | 6/20 | 0.91 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778577 | 0.95 | MAOB (1.00) | MAOBMAOANR4A2ALDH1A1HTT | |
| SCHEMBL6054433 | 0.86 | MAOB (0.82) | MAOBMAOANR4A2ALDH1A1HTT | |
| SCHEMBL9126144 | 0.84 | MAOB (0.90) | MAOBMAOANR4A2ALDH1A1HTT | |
| SCHEMBL9328556 | 0.82 | KMT2A (0.66) | MAOBMAOAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL933577 | 0.81 | MAOB (0.76) | MAOBMAOAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1369316 | 0.81 | NR4A2 (1.00) | MAOBMAOANR4A2SMN1; SMN2NPC1 | |
| SCHEMBL1092229 | 0.81 | MAOB (1.00) | MAOBMAOAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11762738 | 0.81 | MAOB (0.73) | MAOBMAOANR4A2ALDH1A1SMN1; SMN2 | |
| 4-Chloro-Benzoic Acid SCHEMBL7852500 | 0.81 | NR4A2 (0.80) | MAOBMAOANR4A2SMN1; SMN2NPC1 | |
| SCHEMBL18477949 | 0.80 | MAOB (0.73) | MAOBMAOANR4A2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288297-B1 | OPTICALLY ACTIVE BENZENE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4985590-A | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |