Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.59 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.59 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126144 | 0.95 | MAOB (0.90) | MAOBSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL42302 | 0.90 | MAOB (1.00) | MAOBSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL13513249 | 0.90 | MAOB (0.87) | MAOBSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL11845043 | 0.88 | MAOB (0.82) | MAOBSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL29154487 | 0.88 | ALDH1A1 (0.83) | MAOBSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL7737574 | 0.87 | MAOB (0.62) | MAOBSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL5582767 | 0.87 | NR4A2 (0.81) | MAOBSMN1; SMN2FFAR1NR4A1NR4A2 | |
| SCHEMBL1756343 | 0.87 | NR4A2 (0.81) | MAOBSMN1; SMN2FFAR1NR4A1NR4A2 | |
| SCHEMBL7539817 | 0.87 | SRD5A2 (0.73) | MAOBSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL9547816 | 0.86 | MAOB (0.91) | MAOBSMN1; SMN2ALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092190-A2 | METHODS AND COMPOSITIONS FOR MODULATING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ACTIVITY | PRAECIS PHARMACEUTICALS, INC. (US) | 2007-08-16 | — | — | WO | disclosed |
| US-20060223866-A1 | Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity | PRAECIS PHARMACEUTICALS, INC. (US) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223866-A1 | Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity | S1PR1, S1PR2, S1PR3 | MAOB 2920/4885SMN1; SMN2 1924/4885ALDH1A1 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.