Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.64 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | GJB2 | P29033 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21064349 | 0.80 | BCHE (0.44) | BCHEACHEPDPK1MTOR | |
| SCHEMBL18463270 | 0.80 | BCHE (0.45) | BCHEACHEPDPK1MTORTSHR | |
| SCHEMBL24376571 | 0.78 | BCHE (1.00) | BCHEACHEPDPK1MTORLMNA | |
| SCHEMBL18961290 | 0.78 | BCHE (1.00) | BCHEACHEPDPK1MTORLMNA | |
| SCHEMBL8969562 | 0.74 | BCHE (0.80) | BCHEACHEPDPK1MTORLMNA | |
| SCHEMBL20662286 | 0.74 | BCHE (0.51) | BCHEACHEPDPK1MTORTACR2 | |
| Ammonia Solution, Strong SCHEMBL8992146 | 0.73 | BCHE (0.78) | BCHEACHELMNAGJB2 | |
| SCHEMBL18797793 | 0.71 | BCHE (0.48) | BCHEACHEPDPK1MTORLMNA | |
| SCHEMBL24465178 | 0.71 | BCHE (0.48) | BCHEACHEPDPK1MTORLMNA | |
| SCHEMBL18661883 | 0.71 | BCHE (0.48) | BCHEACHEPDPK1MTORLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200523-A | Synthesis of nojirimycin derivatives | MONSANTO COMPANY (US) | 1993-04-06 | — | — | US | claimed |
| US-5248779-A | Synthesis of nojirimycin derivatives | MONSANTO COMPANY (US) | 1993-09-28 | — | — | US | disclosed |
| US-5200523-A | Synthesis of nojirimycin derivatives | MONSANTO COMPANY (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0423099-A1 | Synthesis of nojirimycin derivatives | Monsanto Company (US) | 1991-04-17 | — | — | EP | disclosed |