Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548102 | 0.86 | MAPT (0.69) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9547985 | 0.85 | MAPT (0.68) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9548090 | 0.80 | MAPT (0.68) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9548127 | 0.79 | MAPT (0.67) | MAPTALDH1A1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL9547998 | 0.77 | MAPT (0.68) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL6546546 | 0.76 | MAPT (0.88) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL206504 | 0.76 | MAPT (0.82) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9548024 | 0.76 | MAPT (0.63) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9548072 | 0.76 | MAPT (0.63) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL27431503 | 0.75 | PTGS2 (0.66) | MAPTALDH1A1LMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217971-A | Anticoagulants, hypotensive agents, antiallergens and antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0377457-A1 | Thiazole compounds, processes for the preparation thereof, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |