Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647475 | 0.97 | TSHR (0.52) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL15120651 | 0.93 | TSHR (0.48) | TSHRALDH1A1MGAMGAASI | |
| Cyanide SCHEMBL27906973 | 0.91 | TSHR (0.46) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL27600924 | 0.91 | TSHR (0.46) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL28259310 | 0.87 | TSHR (0.42) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL11756126 | 0.84 | TSHR (0.61) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL662653 | 0.83 | TSHR (0.50) | TSHRALDH1A1MGAMGAASI | |
| Dimethyl Succinate SCHEMBL28792466 | 0.82 | TSHR (0.68) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL4652664 | 0.81 | — | — | |
| SCHEMBL3142044 | 0.81 | POLB (0.58) | TSHRALDH1A1POLBPOLA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252422-A | Method for preparing an electrophotographic photoreceptor | FUJI XEROX CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |