Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548176 | 0.97 | TSHR (0.50) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL15120651 | 0.95 | TSHR (0.48) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL27600924 | 0.93 | TSHR (0.46) | TSHRALDH1A1MGAMGAASI | |
| Cyanide SCHEMBL27906973 | 0.93 | TSHR (0.46) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL28259310 | 0.89 | TSHR (0.42) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL11756126 | 0.86 | TSHR (0.61) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL662653 | 0.85 | TSHR (0.50) | TSHRALDH1A1MGAMGAASI | |
| Dimethyl Succinate SCHEMBL28792466 | 0.84 | TSHR (0.68) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL3142044 | 0.83 | POLB (0.58) | TSHRALDH1A1POLBPOLA1LMNA | |
| SCHEMBL9736888 | 0.82 | TSHR (0.65) | TSHRALDH1A1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117613432-B | Aqueous zinc ion battery composite electrolyte and preparation method and application thereof | 中南大学 | 2024-04-09 | — | — | CN | claimed |
| CN-117613432-A | Containing acyl esters C having both keto and ester groups 5~8 Aqueous zinc ion battery composite electrolyte of alkane chain-like organic additive, and preparation method and application thereof | 中南大学 | 2024-02-27 | — | — | CN | claimed |
| CN-112135820-B | Novel process for preparing diaminopyrimidine derivatives or acid addition salts thereof | 柳韩洋行 | 2024-01-02 | — | — | CN | claimed |
| CN-107876092-B | Application of titanium catalyst with cyclic structure as reaction catalyst for synthesizing benzyl carbonate or diphenyl carbonate by ester exchange | 华东理工大学 | 2023-01-10 | — | — | CN | claimed |
| EP-4069792-A1 | MICHAEL REACTION-CURING HYBRID SYSTEM FOR USE IN CHEMICAL FASTENING TECHNOLOGY | fischerwerke GmbH & Co. KG (DE) | 2022-10-12 | — | — | EP | claimed |
| US-11434224-B2 | Processes for preparing a diaminopyrimidine derivative or acid addition salt thereof | YUHAN CORPORATION (KR) | 2022-09-06 | — | — | US | claimed |
| CN-114729224-A | Michael addition hardening hybrid system for chemical fixation technology | 费希尔厂有限责任两合公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114656633-A | Dihydropyridine polymer and preparation method thereof | 兰州金睿合新材料科技有限责任公司 | 2022-06-24 | — | — | CN | claimed |
| US-20210206746-A1 | NOVEL PROCESSES FOR PREPARING A DIAMINOPYRIMIDINE DERIVATIVE OR ACID ADDITION SALT THEREOF | YUHAN CORPORATION (KR) | 2021-07-08 | — | — | US | claimed |
| WO-2021110621-A1 | MICHAEL REACTION-CURING HYBRID SYSTEM FOR USE IN CHEMICAL FASTENING TECHNOLOGY | FISCHERWERKE GMBH & CO. KG (DE) | 2021-06-10 | — | — | WO | claimed |
| CN-112135820-A | Novel process for preparing diaminopyrimidine derivatives or their acid addition salts | 柳韩洋行 | 2020-12-25 | — | — | CN | claimed |
| CN-108329260-A | A kind of preparation method of Rui Gefeini compounds | 山东罗欣药业集团恒欣药业有限公司 | 2018-07-27 | — | — | CN | claimed |
| CN-107876092-A | The high stability titanium catalyst of ester exchange carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2018-04-06 | — | — | CN | claimed |
| CN-107417719-A | A kind of titanium chelate catalyst for being used for carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2017-12-01 | — | — | CN | claimed |
| CN-104744256-A | Methods for preparing 2-(alkoxylalkylene)-3-oxocarboxylate and pyrimidine compound and application of iron used as catalyst | BEIJING LAVIANA PHARMATECH CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-104557738-A | Green synthesis method of 4(3H)-quinazolinone | UNIV HUNAN | 2015-04-29 | — | — | CN | claimed |
| CN-101657759-B | Alkali-developable photosensitive resin composition and beta-diketone | ADEKA CORP | 2012-07-25 | — | — | CN | claimed |
| US-7560550-B2 | Method for the production of OH protected[4-(2.6-diamino-9H-purine-9-yl)-1.3-dioxolane-2-yl]methanol derivatives | RFS PHARMA, LLC (US) | 2009-07-14 | — | — | US | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| US-4209467-A | COBALT COMPLEX CATALYST | DAICEL LTD. (JP) | 1980-06-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434224-B2 | Processes for preparing a diaminopyrimidine derivative or acid addition salt thereof | HTR4, SLC6A4, HTR5A | TSHR 379/4885ALDH1A1 1406/4885MGAM 3699/4885 |
| US-20210206746-A1 | NOVEL PROCESSES FOR PREPARING A DIAMINOPYRIMIDINE DERIVATIVE OR ACID ADDITION SALT THEREOF | HTR4, SLC6A4, HTR5A | TSHR 397/4885ALDH1A1 1346/4885MGAM 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.