Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28725099 | 1.00 | FFAR3 (0.70) | — | |
| Acetic Acid SCHEMBL6315258 | 0.88 | — | — | |
| Acetic Acid SCHEMBL1079004 | 0.86 | — | — | |
| Acetic Acid SCHEMBL3440778 | 0.84 | — | — | |
| Acetic Acid SCHEMBL11186790 | 0.84 | FFAR3 (0.78) | — | |
| Acetic Acid SCHEMBL9525105 | 0.84 | FFAR3 (0.78) | — | |
| Acetic Acid SCHEMBL2451995 | 0.84 | FFAR3 (0.78) | — | |
| Acetic Acid SCHEMBL4727091 | 0.84 | FFAR3 (0.78) | — | |
| Acetic Acid SCHEMBL5071219 | 0.84 | FFAR3 (0.78) | — | |
| Acetic Acid SCHEMBL9523969 | 0.84 | FFAR3 (0.78) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107646834-A | The dispersible oily suspension formulation and preparation method of a kind of modification | 广东中迅农科股份有限公司 | 2018-02-02 | — | — | CN | claimed |
| EP-2807142-B1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC (US) | 2019-09-04 | — | — | EP | disclosed |
| CN-104193765-B | A kind of synthetic method of cefixime | 浙江普洛得邦制药有限公司 | 2016-08-17 | — | — | CN | disclosed |
| US-20150158807-A1 | METHYLIDENE MALONATE PROCESS | H.B. FULLER COMPANY, AS COLLATERAL AGENT | 2015-06-11 | — | — | US | disclosed |
| EP-2807142-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | Optmed Inc. (US) | 2014-12-03 | — | — | EP | disclosed |
| US-20130197264-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| WO-2013113035-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED, INC. (US) | 2013-08-01 | — | — | WO | disclosed |
| US-5227414-A | For concrete floors, endcapping urethane with ketimine, hydrolysis, reaction with epoxy | TENNANT COMPANY (US) | 1993-07-13 | — | — | US | disclosed |