Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 2/20 | 0.56 |
| ▸ | CPA1 | P15085 | 8/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.48 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971997 | 0.84 | KDM4E (0.46) | CPA1 | |
| SCHEMBL14960661 | 0.83 | CPA1 (0.53) | CPA3CPA1KEAP1CYP1A2CPB1 | |
| SCHEMBL8765867 | 0.81 | CYP1A2 (0.47) | FFAR1MMECYP1A2 | |
| SCHEMBL9544466 | 0.81 | CYP1A2 (0.47) | FFAR1MMECYP1A2 | |
| SCHEMBL9756637 | 0.81 | CPA1 (0.49) | CPA1CYP1A2 | |
| SCHEMBL9356423 | 0.79 | CPA1 (0.44) | CPA1 | |
| SCHEMBL27988988 | 0.79 | CPA1 (0.44) | CPA3CPA1CYP1A2 | |
| SCHEMBL6014438 | 0.79 | CPA1 (0.44) | CPA1 | |
| SCHEMBL28259287 | 0.79 | CPA1 (0.50) | CPA1CYP1A2 | |
| SCHEMBL5981148 | 0.79 | CPA1 (0.50) | CPA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273989-A | 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |