Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10968235 | 0.95 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL28948213 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL19618994 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL18673 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL3963428 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL4941879 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL2926392 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL20624816 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL118235 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL28434793 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273989-A | 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| CN-1055537-A | 3, two replacement-2-different azoles alkane of 5-and different azoles, its preparation method contain the preparation and the application thereof of this composition | HOECHST AG (DE) | 1991-10-23 | — | — | CN | disclosed |