SCHEMBL9548440

SCHEMBL9548440

NCC(=O)N(CCO)c1c(I)c(C(N)=O)c(I)c(C(=O)N(CC(O)CO)CC(O)CO)c1I

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380649 0.92 CYP2C19 (0.41) CYP2C19HIF1ALMNA
SCHEMBL5030981 0.89 CYP2C19 (0.40) CYP2C19HIF1ALMNA
SCHEMBL9189582 0.88 CYP2C19 (0.40) CYP2C19HIF1ALMNA
SCHEMBL9196450 0.85 CYP2C19 (0.42) CYP2C19HIF1ALMNA
SCHEMBL9736246 0.84 CYP2C19 (0.45) CYP2C19HIF1ALMNA
SCHEMBL9194273 0.83 CYP2C19 (0.51) CYP2C19HIF1ALMNA
SCHEMBL9194250 0.82 CYP2C19 (0.56) CYP2C19HIF1ALMNA
SCHEMBL1856683 0.81 CYP2C19 (0.60) CYP2C19HIF1ALMNA
SCHEMBL7986119 0.81 LMNA (0.58) CYP2C19HIF1ALMNA
SCHEMBL9581171 0.80 CYP2C19 (0.42) CYP2C19HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993010825-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT MEDICAL, INC. (US) 1993-06-10 WO disclosed
US-5177261-A SYNTHESIS OF IOVERSOL USING CHLOROACETYL CHLORIDE MALLINCKRODT MEDICAL, INC. (US) 1993-01-05 US disclosed
EP-0504266-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT, INC. (US) 1992-09-23 EP disclosed
WO-1991009007-A2 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT, INC. (US) 1991-06-27 WO disclosed