Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548487 | 0.92 | ELANE (0.44) | ELANEGRM2TBXAS1F10MMP1 | |
| SCHEMBL9548455 | 0.83 | ELANE (0.42) | ELANEGRM2TBXAS1F10MMP1 | |
| SCHEMBL9689243 | 0.69 | ELANE (0.43) | ELANEMMP1MMP9CASP3KMT2A | |
| SCHEMBL9690431 | 0.68 | ELANE (0.38) | ELANEMMP1MMP9CASP3KMT2A | |
| SCHEMBL9432185 | 0.68 | ELANE (0.38) | ELANEMMP1MMP9CASP3KMT2A | |
| SCHEMBL9690422 | 0.67 | ELANE (0.39) | ELANEMMP1MMP9CASP3KMT2A | |
| SCHEMBL23258853 | 0.67 | ELANE (0.37) | ELANEMMP1MMP9CASP3KMT2A | |
| SCHEMBL9431775 | 0.67 | ELANE (0.37) | ELANEMMP1MMP9CASP3KMT2A | |
| SCHEMBL25601214 | 0.67 | ELANE (0.37) | ELANEMMP1MMP9CASP3KMT2A | |
| SCHEMBL10591851 | 0.67 | ELANE (0.36) | ELANETBXAS1MMP1MMP9CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336143-B1 | A NEW PROCESS FOR CARBAPENEM INTERMEDIATES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4960879-A | REACTING SUBSTITUTED AZETIDINONE WITH TRANS SUBSTITUTED-METHYL ALKYLACRYLIC ACID AND REDUCING METAL | SHIONOGI & CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0336143-A1 | A new process for carbapenem intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-10-11 | — | — | EP | disclosed |