Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548489 | 1.00 | GRIK1 (0.37) | GRIK1GRIK2ALDH1A1TRPA1GSK3B | |
| SCHEMBL8472814 | 0.83 | GRIK1 (0.41) | GRIK1GRIK2ALDH1A1TRPA1 | |
| SCHEMBL8472817 | 0.83 | GRIK1 (0.41) | GRIK1GRIK2ALDH1A1TRPA1 | |
| SCHEMBL5331456 | 0.82 | GRIK1 (0.35) | GRIK1GRIK2ALDH1A1TET2EGLN1 | |
| SCHEMBL5331451 | 0.82 | GRIK1 (0.35) | GRIK1GRIK2ALDH1A1TET2EGLN1 | |
| SCHEMBL10062277 | 0.82 | GRIK1 (0.35) | GRIK1GRIK2ALDH1A1TET2EGLN1 | |
| SCHEMBL5963393 | 0.81 | ALDH1A1 (0.46) | GRIK1GRIK2ALDH1A1TRPA1EGLN1 | |
| SCHEMBL5963394 | 0.81 | ALDH1A1 (0.46) | GRIK1GRIK2ALDH1A1TRPA1EGLN1 | |
| SCHEMBL16881887 | 0.80 | GRIK1 (0.44) | GRIK1GRIK2 | |
| SCHEMBL10525151 | 0.80 | GRIK1 (0.34) | GRIK1GRIK2ALDH1A1TET2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073885-B2 | Vitamin D3 lactone derivatives | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| US-9073885-B2 | Vitamin D3 lactone derivatives | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-0336143-B1 | A NEW PROCESS FOR CARBAPENEM INTERMEDIATES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-06-09 | — | — | EP | disclosed |