Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566949 | 1.00 | TSHR (0.40) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL4820346 | 1.00 | TSHR (0.40) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL4824687 | 0.88 | SELP (0.39) | TSHRKMT2APTPN1 | |
| SCHEMBL7574353 | 0.84 | TSHR (0.59) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL8935607 | 0.84 | TSHR (0.59) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL4881651 | 0.84 | TSHR (0.59) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL7566645 | 0.84 | TSHR (0.59) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL7565147 | 0.84 | TSHR (0.59) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL23563202 | 0.83 | ALDH1A1 (0.39) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL9300189 | 0.83 | ALDH1A1 (0.39) | TSHRLMNAKMT2ACYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993008205-A1 | PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-04-29 | — | — | WO | claimed |