Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 7/20 | 0.45 |
| ▸ | TOP2A | P11388 | 4/20 | 0.43 |
| ▸ | TK2 | O00142 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548643 | 1.00 | TK1 (0.45) | TK1TOP2ATK2ALBPKM | |
| SCHEMBL12942600 | 0.94 | TK1 (0.46) | TK1TOP2A | |
| SCHEMBL9548698 | 0.94 | TK1 (0.46) | TK1TOP2A | |
| SCHEMBL9548691 | 0.94 | TK1 (0.46) | TK1TOP2A | |
| SCHEMBL25400182 | 0.91 | TK1 (0.45) | TK1TOP2A | |
| SCHEMBL26274379 | 0.91 | TK1 (0.45) | TK1TOP2A | |
| SCHEMBL8932095 | 0.91 | TOP2A (0.43) | TK1TOP2A | |
| SCHEMBL1417620 | 0.88 | TOP2A (0.41) | TK1TOP2A | |
| SCHEMBL9548856 | 0.87 | TOP2A (0.41) | TK1TOP2A | |
| SCHEMBL9548859 | 0.87 | TOP2A (0.41) | TK1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |