Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057086 | 0.96 | DRD2 (0.50) | DRD2DRD3TAAR1CYP1A2CYP2C9 | |
| SCHEMBL3359014 | 0.87 | DRD2 (0.53) | DRD2DRD3TAAR1CYP1A2CYP2C9 | |
| SCHEMBL12887154 | 0.86 | DRD2 (0.49) | DRD2DRD3TAAR1HPGDPTGES | |
| SCHEMBL15412780 | 0.85 | TAAR1 (0.47) | DRD2DRD3TAAR1HPGDPTGES | |
| SCHEMBL9548899 | 0.85 | TAAR1 (0.47) | DRD2DRD3TAAR1HPGDPTGES | |
| SCHEMBL9516504 | 0.85 | TAAR1 (0.47) | DRD2DRD3TAAR1HPGDPTGES | |
| SCHEMBL10764302 | 0.84 | DRD2 (0.50) | DRD2DRD3TAAR1HPGDPTGES | |
| SCHEMBL479753 | 0.83 | DRD2 (0.41) | DRD2DRD3TAAR1CYP1A2CYP2C9 | |
| SCHEMBL19474668 | 0.82 | DRD2 (0.49) | DRD2DRD3TAAR1HPGDPTGES | |
| SCHEMBL15412417 | 0.81 | DRD2 (0.47) | DRD2DRD3TAAR1HPGDPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204424-A | CONDUCTIVE POLYMERS DERIVED FROM AROMATIC HETEROCYCLIC COMPOUNDS SUBSTITUTED BY AN ETHER-TYPE GROUP | SOLVAY S.A. (BE) | 1993-04-20 | — | — | US | disclosed |