Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549039 | 1.00 | CYP19A1 (0.50) | CYP19A1ESR1ALDH1A1MAOBABCG2 | |
| SCHEMBL9549035 | 1.00 | CYP19A1 (0.50) | CYP19A1ESR1ALDH1A1MAOBABCG2 | |
| SCHEMBL9549238 | 0.95 | ALDH1A1 (0.51) | ALDH1A1MAOBMAPTNPC1KDM4E | |
| SCHEMBL9549325 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAOBMAPTNPC1KDM4E | |
| SCHEMBL9549320 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAOBMAPTNPC1KDM4E | |
| SCHEMBL9548997 | 0.88 | NPC1 (0.54) | ALDH1A1MAOBMAPTNPC1KDM4E | |
| SCHEMBL9549165 | 0.86 | PDE4B (0.49) | CYP19A1ESR1ALDH1A1MAPTNPC1 | |
| SCHEMBL9549180 | 0.86 | PDE4B (0.49) | CYP19A1ESR1ALDH1A1MAPTNPC1 | |
| SCHEMBL9549159 | 0.86 | PDE4B (0.49) | CYP19A1ESR1ALDH1A1MAPTNPC1 | |
| SCHEMBL9549069 | 0.86 | CYP19A1 (0.47) | CYP19A1ESR1ALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206403-A | Diphenylethylene derivatives, pharmaceutical compositions containing same and treatment methods | EISAI CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5182301-A | Anticoagulants | EISAI CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| US-5103010-A | DIPHENYLETHYLENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND TREATMENT METHOD | EISAI CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5064848-A | Anticoagulants | EISAI CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| US-4978767-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1990-12-18 | — | — | US | disclosed |
| US-4954523-A | ANTICOAGULANT | EISAI CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4886834-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |