Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24412631 | 0.89 | HPGD (0.66) | EPHX2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL11666142 | 0.86 | GAA (0.57) | EPHX2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9320586 | 0.84 | ACKR3 (0.64) | EPHX2HPGDDNM1 | |
| SCHEMBL25228045 | 0.83 | SIRT2 (0.57) | EPHX2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL9872490 | 0.83 | ACKR3 (0.63) | EPHX2HPGDDNM1 | |
| Hydrochloric Acid SCHEMBL27718505 | 0.83 | ACKR3 (0.63) | EPHX2HPGDDNM1 | |
| SCHEMBL8781086 | 0.83 | MTNR1A (0.52) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL17101321 | 0.82 | APP (0.53) | EPHX2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1456740 | 0.81 | EPHX2 (0.80) | EPHX2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL19043177 | 0.81 | EPHX2 (0.80) | EPHX2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288515-B1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | ISP INVESTMENTS INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| US-4837013-A | VISCOSITY ENHANCING AND HAIR CONDITIONING PROPERTIES | GAF CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |