SCHEMBL9549348

SCHEMBL9549348

CCCCCCCCCCCCOCCN(CCOCCCCCCCCCCCC)CCOCCCCCCCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.54
THRB P10828 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
MAPT P10636 1/20 0.54
CES2 O00748 2/20 0.45
ZDHHC20 Q5W0Z9 1/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
USP2 O75604 1/20 0.42
SPHK1 Q9NYA1 1/20 0.41
CES1 P23141 1/20 0.41
DNM1 Q05193 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10422513 1.00 HTT (0.54) HTTTHRBMEN1KMT2AMAPT
SCHEMBL12120261 1.00 HTT (0.54) HTTTHRBMEN1KMT2AMAPT
SCHEMBL12120266 1.00 HTT (0.54) HTTTHRBMEN1KMT2AMAPT
SCHEMBL12120263 1.00 HTT (0.54) HTTTHRBMEN1KMT2AMAPT
Hydrochloric Acid SCHEMBL10723993 0.98 HTT (0.52) HTTTHRBMEN1KMT2AMAPT
SCHEMBL64901 0.97 HTT (0.50) HTTTHRBMEN1KMT2AMAPT
SCHEMBL19637028 0.95 MEN1 (0.50) HTTTHRBMEN1KMT2AMAPT
Hypochlorous Acid SCHEMBL10724008 0.93 HTT (0.54) HTTTHRBMEN1KMT2AMAPT
SCHEMBL10731682 0.91 MEN1 (0.50) HTTTHRBMEN1KMT2AMAPT
SCHEMBL19554736 0.91 HTT (0.50) HTTTHRBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0288515-B1 QUATERNIZED NITROGEN CONTAINING COMPOUNDS ISP INVESTMENTS INC. (US) 1993-05-05 EP disclosed
EP-0288515-A4 QUATERNIZED NITROGEN CONTAINING COMPOUNDS 1990-09-26 EP disclosed
US-4830850-A CONDITIONERS, SOFTENERS, PRESERVATIVES GAF CORPORATION (US) 1989-05-16 US disclosed
EP-0288515-A1 QUATERNIZED NITROGEN CONTAINING COMPOUNDS. GAF CORP (US) 1988-11-02 EP disclosed
WO-1988002985-A1 QUATERNIZED NITROGEN CONTAINING COMPOUNDS GAF CORPORATION (US) 1988-05-05 WO disclosed
US-4650865-A Process for preparing tertiary ether amines HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1987-03-17 US disclosed
EP-0190708-A1 Process for the preparation of tertiary ether amines Henkel Kommanditgesellschaft auf Aktien (DE) 1986-08-13 EP disclosed