Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549348 | 0.95 | HTT (0.54) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL12120266 | 0.95 | HTT (0.54) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL12120261 | 0.95 | HTT (0.54) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL10422513 | 0.95 | HTT (0.54) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL12120263 | 0.95 | HTT (0.54) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9705223 | 0.95 | DNM1 (0.46) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9549114 | 0.95 | HTT (0.54) | MEN1THRBHTTKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL10723993 | 0.93 | HTT (0.52) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL64901 | 0.93 | HTT (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL27445853 | 0.91 | DNM1 (0.42) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201347-A1 | POLYNUCLEOTIDES ENCODING CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR FOR THE TREATMENT OF CYSTIC FIBROSIS | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |