Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990250 | 0.65 | — | — | |
| SCHEMBL4683154 | 0.61 | BRD4 (0.30) | — | |
| SCHEMBL4675858 | 0.59 | — | — | |
| SCHEMBL11585697 | 0.58 | GRIK1 (0.30) | GRIK1GRIK2 | |
| SCHEMBL11585691 | 0.58 | GRIK1 (0.30) | GRIK1GRIK2 | |
| SCHEMBL11857180 | 0.57 | GRIK1 (0.54) | GRIK1GRIK2 | |
| SCHEMBL2917234 | 0.57 | GRIK1 (0.54) | GRIK1GRIK2 | |
| Acetic Acid SCHEMBL30976733 | 0.56 | GRIK1 (0.44) | GRIK1GRIK2 | |
| SCHEMBL5314429 | 0.56 | — | — | |
| SCHEMBL5314427 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236899-A | Enhanced sensitivity to antitumor agents | MERCK & CO., INC. (US) | 1993-08-17 | — | — | US | disclosed |
| US-5227467-A | Containing fluorinated valine residue | MERCK & CO., INC. (US) | 1993-07-13 | — | — | US | disclosed |
| US-4914188-A | ANTIBODY INHIBITORS | MERCK & CO., INC. (US) | 1990-04-03 | — | — | US | disclosed |