Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69740 | 0.84 | NR4A2 (0.48) | KDM4EPOLBGAAHSD17B10TSHR | |
| SCHEMBL5154077 | 0.80 | NOTUM (0.52) | KDM4EHSD17B10MAPTALDH1A1KMT2A | |
| SCHEMBL3563589 | 0.77 | MAPT (0.55) | KDM4EPOLBGAAHSD17B10TSHR | |
| SCHEMBL261551 | 0.76 | NOTUM (0.52) | KDM4EPOLBGAAHSD17B10TSHR | |
| SCHEMBL1155989 | 0.76 | NOTUM (0.58) | KDM4EPOLBGAAHSD17B10TSHR | |
| SCHEMBL30859597 | 0.75 | KDM4E (0.47) | KDM4EPOLBGAAHSD17B10MAPT | |
| SCHEMBL7378524 | 0.75 | KDM4E (0.73) | KDM4EPOLBGAAHSD17B10TSHR | |
| SCHEMBL6582728 | 0.75 | KDM4E (0.67) | KDM4EPOLBGAAHSD17B10MAPT | |
| SCHEMBL21367044 | 0.74 | NR4A2 (0.45) | KDM4EPOLBGAAHSD17B10TSHR | |
| SCHEMBL721113 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194382-A | — | — | None | — | — | JP | disclosed |
| JP-H05194382-A | NEW PYRROLE COMPOUND, ITS PRODUCTION AND ITS POLYMER | NIPPON SODA CO LTD | 1993-08-03 | — | — | JP | disclosed |