Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466908 | 0.95 | KDM4E (0.68) | KDM4EGAAPOLBKMT2AHSD17B10 | |
| SCHEMBL6582726 | 0.91 | LCK (0.60) | KDM4EGAAPOLBKMT2AHSD17B10 | |
| SCHEMBL7378524 | 0.90 | KDM4E (0.73) | KDM4EGAAPOLBKMT2AHSD17B10 | |
| SCHEMBL6781993 | 0.89 | KDM4E (0.56) | KDM4EGAAPOLBKMT2AHSD17B10 | |
| SCHEMBL11568484 | 0.88 | KDM4E (0.76) | KDM4EGAAPOLBKMT2AHSD17B10 | |
| SCHEMBL11317879 | 0.88 | GAA (0.72) | KDM4EGAAPOLBKMT2AHSD17B10 | |
| SCHEMBL2900351 | 0.88 | KDM4E (0.82) | KDM4EGAAPOLBKMT2AHSD17B10 | |
| SCHEMBL23704095 | 0.85 | GAA (0.54) | KDM4EGAAPOLBKMT2AHSD17B10 | |
| SCHEMBL19219043 | 0.85 | KDM4E (0.55) | KDM4EGAAPOLBKMT2AHSD17B10 | |
| SCHEMBL6473999 | 0.85 | GAA (0.74) | KDM4EGAAPOLBKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293907-B | High molecular weight polyester based on biomass as monomer, preparation method and application | 武汉科技大学 | 2020-12-29 | — | — | CN | claimed |
| CN-108623795-B | Polyester based on full biomass monomer, preparation method and application | 武汉科技大学 | 2020-11-06 | — | — | CN | claimed |
| CN-109293907-A | It is a kind of based on biomass be monomer high molecular weight polyesters, Preparation method and use | 武汉科技大学 | 2019-02-01 | — | — | CN | claimed |
| CN-108623795-A | A kind of polyester, Preparation method and use based on full biomass monomer | 武汉科技大学 | 2018-10-09 | — | — | CN | claimed |
| US-20240339644-A1 | Symmetric Redox Molecules Using Synergistic Electron Directing Pairs | ExxonMobil Technology and Engineering Company (US) | 2024-10-10 | — | — | US | disclosed |
| CN-109293907-B | High molecular weight polyester based on biomass as monomer, preparation method and application | 武汉科技大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-109293907-B | High molecular weight polyester based on biomass as monomer, preparation method and application | 武汉科技大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-108623795-B | Polyester based on full biomass monomer, preparation method and application | 武汉科技大学 | 2020-11-06 | — | — | CN | disclosed |
| CN-108623795-B | Polyester based on full biomass monomer, preparation method and application | 武汉科技大学 | 2020-11-06 | — | — | CN | disclosed |
| CN-109293907-A | It is a kind of based on biomass be monomer high molecular weight polyesters, Preparation method and use | 武汉科技大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-109293907-A | It is a kind of based on biomass be monomer high molecular weight polyesters, Preparation method and use | 武汉科技大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-108623795-A | A kind of polyester, Preparation method and use based on full biomass monomer | 武汉科技大学 | 2018-10-09 | — | — | CN | disclosed |
| US-20040235930-A1 | Indole derivatives and their use for the treatment of osteoporosis amongst other applications | FARINA CARLO (IT) | 2004-11-25 | — | — | US | disclosed |
| EP-1212317-B1 | INDOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF OSTEOPOROSIS AMONGST OTHER APPLICATIONS | NIKEM RESEARCH SRL (IT) | 2004-09-15 | — | — | EP | disclosed |
| US-6787550-B1 | 4-(5,6-DICHLORO-1H-INDOL-2-YL)-3-ETHOXY-N-(2,2,6,6 -TETRAMETHYLTETRAMETHYLPIPERIDIN-4-YL)-BENZAMIDE | NIKEM RESEARCH S.R.L. (IT) | 2004-09-07 | — | — | US | disclosed |
| EP-1212317-A1 | INDOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF OSTEOPOROSIS AMONGST OTHER APPLICATIONS | GlaxoSmithKline S.p.A. (IT) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001002388-A1 | INDOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF OSTEOPOROSIS AMONGST OTHER APPLICATIONS | GLAXOSMITHKLINE S.P.A. (IT) | 2001-01-11 | — | — | WO | disclosed |
| WO-1997019916-A2 | BISAZO COMPOUNDS, INTERMEDIATES THEREOF, PROCESS FOR SYNTHESIZING THE SAME AND THERAPEUTIC AGENT FOR VIRAL INFECTION CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1997-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235930-A1 | Indole derivatives and their use for the treatment of osteoporosis amongst other applications | MALT1, SOST, NFATC1 | KDM4E 2237/4885GAA 1878/4885POLB 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.