⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532653 | 0.68 | — | — | |
| SCHEMBL766195 | 0.65 | — | — | |
| SCHEMBL4757733 | 0.55 | — | — | |
| SCHEMBL5884621 | 0.50 | — | — | |
| SCHEMBL8277496 | 0.49 | — | — | |
| SCHEMBL12520988 | 0.49 | — | — | |
| SCHEMBL4052707 | 0.49 | — | — | |
| SCHEMBL19100784 | 0.49 | — | — | |
| SCHEMBL5745258 | 0.49 | — | — | |
| SCHEMBL1691032 | 0.41 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10172837-B2 | Insulin sensitisers and methods of treatment | NAIA Metabolic, Inc. (US) | 2019-01-08 | — | — | US | disclosed |
| EP-2106260-B1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | VERVA PHARMACEUTICALS LTD (AU) | 2017-12-06 | — | — | EP | disclosed |
| US-20170079960-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | NAIA Metabolic, Inc. | 2017-03-23 | — | — | US | disclosed |
| US-9452148-B2 | Insulin sensitisers and methods of treatment | VERVA PHARMACEUTICALS LTD (AU) | 2016-09-27 | — | — | US | disclosed |
| US-8455432-B2 | Insulin sensitisers and methods of treatment | VERVA PHARMACEUTICALS LTD. (AU) | 2013-06-04 | — | — | US | disclosed |
| US-20110003740-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | VERVA PHARMACEUTICALS LTD. (AU) | 2011-01-06 | — | — | US | disclosed |
| EP-2106260-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | Verva Pharmaceuticals Ltd (AU) | 2009-10-07 | — | — | EP | disclosed |
| WO-2008089521-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | VERVA PHARMACEUTICALS LTD (AU) | 2008-07-31 | — | — | WO | disclosed |