SCHEMBL9532653

SCHEMBL9532653

C1=CN=C2SC=NN2C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL954957 0.68
SCHEMBL954958 0.67
SCHEMBL31405560 0.61 KMT2A (0.41)
SCHEMBL766195 0.58
SCHEMBL4757733 0.56
SCHEMBL5884621 0.51
SCHEMBL5399391 0.51
SCHEMBL958761 0.50
SCHEMBL19100784 0.50
SCHEMBL12520988 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58134098-A None JP disclosed
US-10174011-B2 Heterocyclic compounds, process for preparation of the same and use thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-08 US disclosed
US-20170158680-A1 HETEROCYCLIC COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2017-06-08 US disclosed
US-20170158680-A1 HETEROCYCLIC COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2017-06-08 US disclosed
EP-3115361-A1 HETEROCYCLIC COMPOUNDS, AND PREPARATION METHOD AND USE THEREOF Shanghai Institute Of Materia Medica Chinese Academy of Sciences (CN) 2017-01-11 EP disclosed
WO-2015131856-A1 HETEROCYCLIC COMPOUNDS, AND PREPARATION METHOD AND USE THEREOF 中国科学院上海药物研究所 2015-09-11 WO disclosed
EP-0238059-B1 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-06-16 EP disclosed
US-4971971-A FUNGICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-11-20 US disclosed
EP-0238997-B1 AGRICULTURAL-HORTICULTURAL FUNGICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-06-20 EP disclosed
US-4866064-A AGRICULTURE HORTICULTURE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-09-12 US disclosed
EP-0282635-A2 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-09-21 EP disclosed
EP-0238059-A2 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-09-23 EP disclosed
US-4537962-A ANTIULCER, ANTISECRETORY AGENTS FARMITALIA CARLO ERBA, S.P.A. (IT) 1985-08-27 US disclosed
US-4537962-A ANTIULCER, ANTISECRETORY AGENTS FARMITALIA CARLO ERBA, S.P.A. (IT) 1985-08-27 US disclosed
US-4522944-A ANTIINFLAMMATORY AGENTS AND PAIN KILLERS FARMITALIA CARLO ERBA S.P.A., MILAN ITALY A CORP OF ITALY (IT) 1985-06-11 US disclosed
US-4522944-A ANTIINFLAMMATORY AGENTS AND PAIN KILLERS FARMITALIA CARLO ERBA S.P.A., MILAN ITALY A CORP OF ITALY (IT) 1985-06-11 US disclosed
JP-S58134098-A SUBSTITUTED 1,3,4-THIADIAZOLO(3,2-A)PYRIMIDINE AND MANUFACTURE ERBA CARLO SPA 1983-08-10 JP disclosed