⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766196 | 0.64 | — | — | |
| SCHEMBL659604 | 0.61 | — | — | |
| SCHEMBL3490997 | 0.58 | NPSR1 (0.36) | — | |
| SCHEMBL958761 | 0.48 | — | — | |
| SCHEMBL6323399 | 0.44 | — | — | |
| SCHEMBL3691228 | 0.42 | — | — | |
| SCHEMBL2298929 | 0.38 | — | — | |
| SCHEMBL5943316 | 0.36 | — | — | |
| SCHEMBL331364 | 0.36 | — | — | |
| SCHEMBL2326 | 0.36 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10172837-B2 | Insulin sensitisers and methods of treatment | NAIA Metabolic, Inc. (US) | 2019-01-08 | — | — | US | disclosed |
| EP-2106260-B1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | VERVA PHARMACEUTICALS LTD (AU) | 2017-12-06 | — | — | EP | disclosed |
| US-20170079960-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | NAIA Metabolic, Inc. | 2017-03-23 | — | — | US | disclosed |
| US-9452148-B2 | Insulin sensitisers and methods of treatment | VERVA PHARMACEUTICALS LTD (AU) | 2016-09-27 | — | — | US | disclosed |
| US-8455432-B2 | Insulin sensitisers and methods of treatment | VERVA PHARMACEUTICALS LTD. (AU) | 2013-06-04 | — | — | US | disclosed |
| US-20110003740-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | VERVA PHARMACEUTICALS LTD. (AU) | 2011-01-06 | — | — | US | disclosed |
| EP-2106260-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | Verva Pharmaceuticals Ltd (AU) | 2009-10-07 | — | — | EP | disclosed |
| WO-2008089521-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | VERVA PHARMACEUTICALS LTD (AU) | 2008-07-31 | — | — | WO | disclosed |