Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549664 | 0.81 | MEN1 (0.56) | TDP1CYP3A4CHRM2CHRM1CHRM3 | |
| SCHEMBL27829034 | 0.79 | CYP3A4 (0.50) | TDP1CYP3A4CHRM2CHRM1CHRM3 | |
| SCHEMBL447607 | 0.79 | CYP3A4 (0.50) | TDP1CYP3A4CHRM2CHRM1CHRM3 | |
| SCHEMBL2646656 | 0.76 | TDP1 (0.57) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| 1,2-Dibromoethane SCHEMBL28837174 | 0.75 | TDP1 (0.71) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL2647450 | 0.75 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL4265559 | 0.74 | MEN1 (0.50) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8723999 | 0.74 | CYP3A4 (0.44) | TDP1CYP3A4LTA4HESR1ESR2 | |
| N-Propyl Bromide SCHEMBL1400032 | 0.73 | TDP1 (0.60) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Bromoethane SCHEMBL43961 | 0.73 | TDP1 (0.67) | TDP1CYP3A4CHRM2CHRM1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208317-A | Molding materials of cured epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5109099-A | ADVANCING EPOXY RESINS IN PRESENCE OF AMINO GROUP-CONTAINING PHOSPHONIUM CATALYST | THE DOW CHEMICAL COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0441243-A2 | Precatalyzed catalyst compositions, process for preparing epoxy resins, curable compositions, articles resulting from curing the resultant compositions | THE DOW CHEMICAL COMPANY (US) | 1991-08-14 | — | — | EP | disclosed |
| US-4981926-A | Rapid and selective curing using phosphonium catalyst containing an amine group; polyepoxides | THE DOW CHEMICAL COMPANY (US) | 1991-01-01 | — | — | US | disclosed |