Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455349 | 0.88 | CYP3A4 (0.46) | CYP3A4TDP1TAAR1HTR2AHRH1 | |
| SCHEMBL10790182 | 0.87 | CYP3A4 (0.60) | CYP3A4TDP1TAAR1HTR2AHRH1 | |
| SCHEMBL9549821 | 0.86 | SIGMAR1 (0.47) | CYP3A4TDP1TAAR1HTR2AHRH1 | |
| Bromide SCHEMBL4353499 | 0.86 | CYP3A4 (0.44) | CYP3A4TDP1TAAR1HTR2AHRH1 | |
| 1,2-Dibromoethane SCHEMBL28837174 | 0.79 | TDP1 (0.71) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL9549741 | 0.79 | CYP3A4 (0.50) | CYP3A4TDP1TAAR1HTR2AHRH1 | |
| SCHEMBL9549561 | 0.79 | CYP3A4 (0.50) | CYP3A4TDP1TAAR1HTR2AHRH1 | |
| Dimethylaminoethanol SCHEMBL134026 | 0.79 | MAPT (0.50) | CYP3A4TDP1TAAR1HTR2AHRH1 | |
| SCHEMBL9549846 | 0.79 | TDP1 (0.44) | CYP3A4TDP1HTR2AHRH1ESR1 | |
| N-Propyl Bromide SCHEMBL1400032 | 0.78 | TDP1 (0.60) | CYP3A4TDP1ESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120201803-A1 | 3-SUBSTITUTED COMPOUNDS FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2012-08-09 | — | — | US | claimed |
| WO-2012037362-A2 | PROCESS FOR SOLID ELECTROLYTIC CAPACITORS USING POLYMER SLURRIES | KEMET ELECTRONICS CORPORATION (US) | 2012-03-22 | — | — | WO | claimed |
| US-20120063063-A1 | PROCESS FOR SOLID ELECTROLYTIC CAPACITORS USING POLYMER SLURRIES | KEMET ELECTRONICS CORPORATION (US) | 2012-03-15 | — | — | US | claimed |
| CN-114496571-A | Method for producing electrolytic capacitor | 钰邦科技股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| EP-3156387-B1 | METHOD OF PREPARING INDENE DERIVATIVES | AQUINOX PHARMACEUTICALS CANADA INC (CA) | 2018-07-25 | — | — | EP | disclosed |
| EP-3156387-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | Aquinox Pharmaceuticals (Canada) Inc. (CA) | 2017-04-19 | — | — | EP | disclosed |
| EP-2277848-B1 | Indene derivatives as pharmaceutical agents | AQUINOX PHARMACEUTICALS CANADA INC (CA) | 2016-09-14 | — | — | EP | disclosed |
| US-20150307426-A9 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | AQUINOX PHARMACEUTICALS INC. (CA) | 2015-10-29 | — | — | US | disclosed |
| US-20140371252-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | AQUINOX PHARMACEUTICALS INC. (CA) | 2014-12-18 | — | — | US | disclosed |
| US-8673975-B2 | Indene derivatives as pharmaceutical agents | AQUINOX PHARMACEUTICALS INC. (CA) | 2014-03-18 | — | — | US | disclosed |
| US-8546448-B2 | 3-substituted compounds for reducing uric acid | WELLSTAT THERAPEUTICS CORPORATION (US) | 2013-10-01 | — | — | US | disclosed |
| US-5760035-A | PIPERIDINE COMPOUNDS SUBSTITUTED WITH AN AMINOALKYL GROUP AND AN ARYLOXYALKYL GROUP, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |
| EP-0720602-B1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1997-07-09 | — | — | EP | disclosed |
| EP-0720602-A1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008535-A1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1995-03-30 | — | — | WO | disclosed |
| US-5208317-A | Molding materials of cured epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5208317-A | Molding materials of cured epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5109099-A | ADVANCING EPOXY RESINS IN PRESENCE OF AMINO GROUP-CONTAINING PHOSPHONIUM CATALYST | THE DOW CHEMICAL COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0441243-A2 | Precatalyzed catalyst compositions, process for preparing epoxy resins, curable compositions, articles resulting from curing the resultant compositions | THE DOW CHEMICAL COMPANY (US) | 1991-08-14 | — | — | EP | disclosed |
| US-4981926-A | Rapid and selective curing using phosphonium catalyst containing an amine group; polyepoxides | THE DOW CHEMICAL COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307426-A9 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | INSRR, INSR, IDO1 | CYP3A4 38/4885TDP1 1586/4885TAAR1 1766/4885 |
| US-20120201803-A1 | 3-SUBSTITUTED COMPOUNDS FOR REDUCING URIC ACID | XDH, NLRP3, ASIC3 | CYP3A4 2472/4885TDP1 2123/4885TAAR1 2182/4885 |
| US-20140371252-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | INSRR, INSR, IDO1 | CYP3A4 38/4885TDP1 1586/4885TAAR1 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.