Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CDH1 | P12830 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195204 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2ACDH1CTNNB1 | |
| SCHEMBL9550216 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2ACDH1CTNNB1 | |
| SCHEMBL9550221 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2ACDH1CTNNB1 | |
| SCHEMBL9550193 | 0.76 | CNR1 (0.45) | SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9191662 | 0.76 | CNR1 (0.45) | SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9550201 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ACDH1CTNNB1 | |
| SCHEMBL9550208 | 0.73 | NPC1 (0.62) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9550207 | 0.73 | NPC1 (0.62) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL11282455 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2CDH1CTNNB1TCF7L2THRB | |
| SCHEMBL9550244 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196541-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-AMINOACRYLIC ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |