Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677842 | 0.80 | MAOA (0.58) | MAOAMAOBNPC1RAB9APTGES | |
| SCHEMBL10573839 | 0.80 | MAOB (0.58) | MAOAMAOBNPC1RAB9APTGES | |
| SCHEMBL9550408 | 0.80 | MAOB (0.58) | MAOAMAOBNPC1RAB9APTGES | |
| SCHEMBL5123575 | 0.80 | MAOB (0.58) | MAOAMAOBNPC1RAB9APTGES | |
| SCHEMBL9550475 | 0.76 | MAOA (0.54) | MAOAMAOBNPC1RAB9APTGES | |
| SCHEMBL30892693 | 0.72 | MAOA (0.66) | MAOAMAOBNPC1RAB9APTGES | |
| SCHEMBL3925053 | 0.71 | ESR2 (1.00) | ESR1ESR2KDM4EMAPT | |
| SCHEMBL31042796 | 0.71 | ESR2 (1.00) | ESR1ESR2KDM4EMAPT | |
| SCHEMBL9550442 | 0.71 | MAOA (0.51) | MAOAMAOBNPC1RAB9ACYP19A1 | |
| SCHEMBL11732417 | 0.70 | MAOB (1.00) | ESR1ESR2MAOAMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182295-A | Miticides, fungicides | ROUSSEL UCLAF (FR) | 1993-01-26 | — | — | US | disclosed |