Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.56 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922778 | 0.82 | ESR1 (0.51) | NTRK1NTRK2MAOBMAOAALDH1A1 | |
| SCHEMBL11730948 | 0.79 | NTRK1 (0.56) | NTRK1NTRK2MAOBMAOAALDH1A1 | |
| SCHEMBL1742227 | 0.79 | CYP1A1 (0.73) | NTRK1NTRK2MAOBALDH1A1KDM4E | |
| SCHEMBL5389654 | 0.78 | NTRK1 (0.55) | NTRK1NTRK2MAOBMAOAALDH1A1 | |
| SCHEMBL10551657 | 0.77 | NTRK1 (0.57) | NTRK1NTRK2ALDH1A1KDM4EMAPT | |
| SCHEMBL3685028 | 0.74 | MAOB (0.63) | MAOBALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9550494 | 0.73 | NTRK1 (0.53) | NTRK1NTRK2MAOAALDH1A1KDM4E | |
| SCHEMBL8800060 | 0.72 | F2RL3 (0.47) | MAOBMAOAKDM4ECYP1A1CYP1A2 | |
| SCHEMBL3933612 | 0.71 | ESR1 (0.47) | MAOBMAOAAPPESR1ESR2 | |
| SCHEMBL3934108 | 0.71 | EGFR (0.50) | NTRK1NTRK2MAOBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182295-A | Miticides, fungicides | ROUSSEL UCLAF (FR) | 1993-01-26 | — | — | US | disclosed |