Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 7/20 | 0.73 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.73 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650874 | 0.85 | CYP1A1 (1.00) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 | |
| SCHEMBL11643109 | 0.83 | MAOB (0.54) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 | |
| SCHEMBL11646604 | 0.82 | CYP1A1 (0.68) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 | |
| SCHEMBL1740996 | 0.81 | ABCG2 (0.71) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 | |
| SCHEMBL11645931 | 0.80 | CYP1A1 (0.71) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 | |
| SCHEMBL11645031 | 0.80 | CYP1A1 (0.53) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 | |
| SCHEMBL11643021 | 0.80 | MAOB (0.62) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 | |
| SCHEMBL11645034 | 0.80 | CYP1A1 (0.71) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 | |
| SCHEMBL9550456 | 0.79 | NTRK1 (0.56) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 | |
| SCHEMBL28045622 | 0.79 | KDM4E (1.00) | CYP1A1CYP1B1ABCG2ABCC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | claimed |
| US-8038466-B1 | Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof | ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) | 2011-10-18 | — | — | US | claimed |
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | disclosed |
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | disclosed |
| US-8038466-B1 | Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof | ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) | 2011-10-18 | — | — | US | disclosed |