Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695229 | 1.00 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9693686 | 1.00 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9190465 | 1.00 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9192229 | 1.00 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9132505 | 1.00 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9130118 | 1.00 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9131696 | 1.00 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9193619 | 1.00 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9471872 | 0.98 | DGKA (0.50) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL9130035 | 0.94 | DGKA (0.51) | DGKADNM1PAMPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5059012-A | — | — | None | — | — | JP | disclosed |
| JP-H0559012-A | PRODUCTION OF IMIDAZOLINE HAVING ESTER GROUP | KAO CORP | 1993-03-09 | — | — | JP | disclosed |
| US-5154841-A | Cyclizing a polyamine with a fatty acid, ester, acyl halide or anhydride, followed by catalytic esterification with fatty acid ester or glycerides; titanium or tin alkoxides, salts, halides or alkyl halide as catalysts | THE PROCTER & GAMBLE COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0375029-A2 | Process for preparing substituted imidazoline fabric conditioning compounds | THE PROCTER & GAMBLE COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |