Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550572 | 1.00 | KCNH2 (0.53) | KCNH2MAPTNPSR1HTTABCC9 | |
| SCHEMBL9550575 | 1.00 | KCNH2 (0.53) | KCNH2MAPTNPSR1HTTABCC9 | |
| SCHEMBL10886491 | 0.95 | KCNH2 (0.49) | KCNH2MAPTNPSR1HTTABCC9 | |
| SCHEMBL10886505 | 0.95 | KCNH2 (0.49) | KCNH2MAPTNPSR1HTTABCC9 | |
| SCHEMBL10886498 | 0.95 | KCNH2 (0.49) | KCNH2MAPTNPSR1HTTABCC9 | |
| Methyl Alcohol SCHEMBL11187636 | 0.88 | KCNH2 (0.49) | KCNH2MAPTNPSR1HTTKMT2A | |
| Methyl Alcohol SCHEMBL11187643 | 0.88 | KCNH2 (0.49) | KCNH2MAPTNPSR1HTTKMT2A | |
| Methyl Alcohol SCHEMBL11187638 | 0.88 | KCNH2 (0.49) | KCNH2MAPTNPSR1HTTKMT2A | |
| SCHEMBL10724313 | 0.87 | KCNH2 (0.49) | KCNH2MAPTNPSR1ABCC9KMT2A | |
| SCHEMBL10724327 | 0.87 | KCNH2 (0.49) | KCNH2MAPTNPSR1ABCC9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095316-B1 | PHARMACEUTICALLY ACTIVE AMINOBENZOPYRANS | BEECHAM GROUP PLC (GB) | 1986-12-03 | — | — | EP | claimed |
| EP-0095316-A1 | Pharmaceutically active aminobenzopyrans | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | claimed |
| EP-0339562-B1 | BENZOPYRAN COMPOUND AND ITS PHARMACEUTICAL USE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0095316-B1 | PHARMACEUTICALLY ACTIVE AMINOBENZOPYRANS | BEECHAM GROUP PLC (GB) | 1986-12-03 | — | — | EP | disclosed |
| US-4568692-A | LOWERING BLOOD PRESSURE | BEECHAM GROUP P.L.C. | 1986-02-04 | — | — | US | disclosed |
| US-4481214-A | 4-Acylaminobenzopyrans useful as anti-hypertensive agents | BEECHAM GROUP P.L.C. (GB) | 1984-11-06 | — | — | US | disclosed |
| EP-0095316-A1 | Pharmaceutically active aminobenzopyrans | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |