Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMO | Q99835 | 3/20 | 0.48 |
| ▸ | MT-CO2 | P00403 | 6/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3791414 | 0.72 | SMO (0.61) | MEN1KMT2ASMOJAK2TYK2 | |
| SCHEMBL5258149 | 0.72 | ITGB1 (0.71) | ITGB1ITGA4 | |
| SCHEMBL5258142 | 0.72 | ITGB1 (0.71) | ITGB1ITGA4 | |
| SCHEMBL4154853 | 0.72 | TYK2 (0.71) | MEN1KMT2ASMOPTGS2JAK2 | |
| SCHEMBL6602761 | 0.71 | TYK2 (0.61) | KMT2ASMOITGB1ITGA4JAK2 | |
| SCHEMBL5260925 | 0.70 | ITGB1 (0.66) | ITGB1ITGA4 | |
| SCHEMBL5260927 | 0.70 | ITGB1 (0.66) | ITGB1ITGA4 | |
| SCHEMBL3237318 | 0.70 | MEN1 (0.75) | MEN1KMT2AMT-CO2RXFP1SIRT2 | |
| SCHEMBL14825061 | 0.70 | SMO (0.76) | MEN1KMT2ASMOJAK2TYK2 | |
| SCHEMBL23864372 | 0.69 | MEN1 (0.65) | MEN1KMT2AMT-CO2TOP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |