Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.35 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589452 | 0.82 | TSHR (0.57) | TSHRKMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7477597 | 0.81 | TSHR (0.52) | TSHRKMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9400327 | 0.77 | TSHR (0.78) | TSHRKMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1535588 | 0.76 | GAA (0.62) | TSHRKMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9243820 | 0.76 | TSHR (0.48) | TSHRKMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL12247788 | 0.75 | NAAA (0.38) | TSHRKMT2AALDH1A1LMNAGAA | |
| SCHEMBL9927137 | 0.74 | TSHR (0.70) | TSHRKMT2AALDH1A1LMNAGAA | |
| SCHEMBL9745635 | 0.74 | KMT2A (0.78) | TSHRKMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL12247789 | 0.74 | — | — | |
| SCHEMBL7476559 | 0.73 | TSHR (0.51) | TSHRKMT2AALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258138-A | Phenothiazine and a 2,2,6,6-tetraalkyl piperazin-4-yl derivative to prevent addition polymerization of a mixture of acrylic monomers including an hydroxyalkyl acrylic ester; colorless | CIBA-GEIGY CORPORATION (US) | 1993-11-02 | — | — | US | disclosed |