Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.83 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL28750632 | 1.00 | TSHR (0.83) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL119783 | 1.00 | TSHR (0.83) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL28270529 | 0.96 | TSHR (0.77) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL28575371 | 0.96 | TSHR (0.77) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL504363 | 0.96 | TSHR (0.77) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL28016270 | 0.96 | TSHR (0.77) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL17351906 | 0.96 | TSHR (0.77) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL28495525 | 0.96 | TSHR (0.77) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL741942 | 0.96 | TSHR (0.91) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL80797 | 0.96 | TSHR (0.91) | TSHRTP53CYP2C9PDE4ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108706633-A | A kind of antimony oxide and preparation method thereof applied to lithium ion battery negative material | 湖南工业大学 | 2018-10-26 | — | — | CN | claimed |
| CN-107755712-A | A kind of method for preparing metal antimony powder | 山东大学 | 2018-03-06 | — | — | CN | claimed |
| CN-104483313-A | Detection solvent and detection method of residual phosphorus on surface of bolt | RITAI SHANGHAI AUTO STANDARD COMPONENT CO LTD | 2015-04-01 | — | — | CN | claimed |
| JP-5210007-A | — | — | None | — | — | JP | disclosed |
| CN-110422902-A | A kind of preparation method for mixing titanium birnessite of efficient process antimony waste water | RES CT FOR ECO ENVIRONMENTAL SCIENCES CAS | 2019-11-08 | — | — | CN | disclosed |
| CN-109562137-A | Methods and compositions for treating conditions associated with abnormal inflammatory responses | 第波生物公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-108706633-A | A kind of antimony oxide and preparation method thereof applied to lithium ion battery negative material | 湖南工业大学 | 2018-10-26 | — | — | CN | disclosed |
| CN-107755712-A | A kind of method for preparing metal antimony powder | 山东大学 | 2018-03-06 | — | — | CN | disclosed |
| CN-104483313-B | Detection solvent and detection method of residual phosphorus on surface of bolt | 日泰（上海）汽车标准件有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-104483313-A | Detection solvent and detection method of residual phosphorus on surface of bolt | RITAI SHANGHAI AUTO STANDARD COMPONENT CO LTD | 2015-04-01 | — | — | CN | disclosed |
| JP-H05210007-A | COLOR FILTER AND ITS PRODUCTION AS WELL AS DISPLAY DEVICE AND PICKUP DEVICE HAVING THIS COLOR FILTER | PHILIPS GLOEILAMPENFAB:NV | 1993-08-20 | — | — | JP | disclosed |