SCHEMBL9550933

SCHEMBL9550933

CC(C)=CC[C@H](O)[C@@H](C)CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.38
GRIK2 Q13002 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.36
FNTA P49354 3/20 0.34
FNTB P49356 3/20 0.34
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
TRPA1 O75762 1/20 0.32
KMT2A Q03164 1/20 0.32
GABRR1 P24046 2/20 0.31
LMNA P02545 1/20 0.31
CACNA2D1 P54289 2/20 0.31
CACNB3 P54284 1/20 0.31
CACNA1C Q13936 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
PGR P06401 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9576393 0.78 SLC22A6 (0.37) GRIK1GRIK2SLC22A6SMN1; SMN2MAPT
SCHEMBL13573121 0.75 SLC22A6 (0.48) SLC22A6ALDH1A1SMN1; SMN2MAPTGABRR1
SCHEMBL1061282 0.75 GRIK1 (0.44) GRIK1GRIK2FNTAFNTBALDH1A1
SCHEMBL6231134 0.75 GRIK1 (0.44) GRIK1GRIK2FNTAFNTBALDH1A1
SCHEMBL6231140 0.75 GRIK1 (0.44) GRIK1GRIK2FNTAFNTBALDH1A1
SCHEMBL5077944 0.75 SLC22A6 (0.50) SLC22A6ALDH1A1SMN1; SMN2MAPTGABRR1
SCHEMBL304303 0.75 SLC22A6 (0.50) SLC22A6ALDH1A1SMN1; SMN2MAPTGABRR1
SCHEMBL19222413 0.73 GRIK1 (0.39) GRIK1GRIK2SLC22A6FNTAFNTB
SCHEMBL23581574 0.72 SLC22A6 (0.43) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
SCHEMBL7562855 0.72 SLC22A6 (0.43) SLC22A6SMN1; SMN2MAPTGABRR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5213814-A None JP disclosed
JP-H05213814-A OPTICALLY ACTIVE CITRONELLIC ACID DERIVATIVE AND ITS PRODUCTION HORIUCHIITAROU SHOTEN:KK 1993-08-24 JP disclosed