Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 3/20 | 0.40 |
| ▸ | FNTB | P49356 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231134 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2FNTAFNTBALDH1A1 | |
| SCHEMBL1061282 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2FNTAFNTBALDH1A1 | |
| SCHEMBL7635671 | 0.79 | ALDH1A1 (0.51) | FNTAFNTBALDH1A1KDM4EATM | |
| SCHEMBL6480491 | 0.79 | ALDH1A1 (0.51) | FNTAFNTBALDH1A1KDM4EATM | |
| SCHEMBL2592558 | 0.77 | TP53 (0.39) | ALDH1A1TP53 | |
| SCHEMBL28068346 | 0.76 | GRIK1 (0.39) | GRIK1GRIK2TP53TSHR | |
| SCHEMBL976765 | 0.76 | GRIK1 (0.39) | GRIK1GRIK2TP53TSHR | |
| SCHEMBL9550933 | 0.75 | GRIK1 (0.38) | GRIK1GRIK2FNTAFNTBALDH1A1 | |
| SCHEMBL16579852 | 0.75 | GRIK1 (0.48) | GRIK1GRIK2FNTAFNTBALDH1A1 | |
| SCHEMBL132111 | 0.75 | GRIK1 (0.48) | GRIK1GRIK2FNTAFNTBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036190-B1 | A METHOD FOR PRODUCING HYDROXYCARBOXYLIC ACIDS BY AUTO-DEGRADATION OF POLYHYDROXYALKANOATES | CHIROBIO INC (KR) | 2005-05-11 | — | — | EP | claimed |