Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173901 | 0.96 | ACE (0.44) | EPHA2KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL31214780 | 0.93 | EPHA2 (0.52) | EPHA2KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL30443975 | 0.91 | ACE (0.45) | EPHA2KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL31039948 | 0.91 | CXCR4 (0.47) | EPHA2KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL30173928 | 0.91 | EPHA2 (0.45) | EPHA2KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL30490593 | 0.89 | OPRK1 (0.45) | EPHA2KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL29743137 | 0.88 | EPHA2 (0.50) | EPHA2ACECXCR4CALCRLOPRM1 | |
| SCHEMBL29802056 | 0.88 | OPRK1 (0.46) | ACEOPRM1OPRK1 | |
| SCHEMBL30422984 | 0.88 | ACE (0.47) | ACECXCR4OPRM1OPRK1 | |
| SCHEMBL30973972 | 0.88 | ACE (0.50) | ACEOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34165-E | Pentapeptide immunoregulators | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-01-19 | — | — | US | disclosed |
| US-4629723-A | IMMUNOREGULATING PEPTIDES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-16 | — | — | US | disclosed |
| EP-0166612-A2 | Potent thymopentin analogs | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-01-02 | — | — | EP | disclosed |