Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | BRD4 | O60885 | 1/20 | 0.74 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.63 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632655 | 0.89 | DRD3 (0.66) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL28251251 | 0.88 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL34292 | 0.88 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL10738656 | 0.88 | DRD3 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL29351730 | 0.88 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL7824014 | 0.88 | DRD3 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11022977 | 0.88 | DRD3 (0.83) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11390037 | 0.88 | DRD3 (0.60) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL9788090 | 0.87 | DRD3 (0.98) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL22698592 | 0.87 | HSD17B10 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251330-B1 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | HOFFMANN LA ROCHE (CH) | 1993-12-01 | — | — | EP | disclosed |
| EP-0285655-B1 | PROCESS FOR THE PREPARATION OF QUINOLINE-CARBOXYLIC ACID DERIVATIVES | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-04-15 | — | — | EP | disclosed |
| US-4935512-A | Process for the preparation of quinoline-carboxylic acid derivatives | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1990-06-19 | — | — | US | disclosed |
| EP-0251330-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1988-01-07 | — | — | EP | disclosed |