Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | PRNP | P04156 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9551834 | 0.93 | ALDH1A1 (0.42) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL9551854 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL9551819 | 0.90 | NOTUM (0.44) | PPARG | |
| SCHEMBL9551848 | 0.90 | ALDH1A1 (0.46) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL7910151 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL7912983 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL9551839 | 0.82 | NOTUM (0.44) | MAPK1 | |
| SCHEMBL9551818 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL9551846 | 0.80 | NOTUM (0.42) | PPARG | |
| SCHEMBL9551861 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EPPARGNCOA2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212189-A | Enzyme inhibitors | WARNER-LAMBERT COMPANY (US) | 1993-05-18 | — | — | US | claimed |
| US-5212189-A | Enzyme inhibitors | WARNER-LAMBERT COMPANY (US) | 1993-05-18 | — | — | US | disclosed |