Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2181329 | 0.92 | HRH3 (0.42) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2177163 | 0.92 | THRA (0.47) | RARBALDH1A1THRATHRBHSD17B10 | |
| SCHEMBL8719472 | 0.91 | HDAC2 (0.51) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9673289 | 0.89 | THRA (0.50) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9670640 | 0.89 | THRA (0.50) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9673266 | 0.89 | THRA (0.50) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9670792 | 0.89 | THRA (0.50) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9552798 | 0.89 | MAOB (0.53) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3311898 | 0.89 | HDAC2 (0.53) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11802202 | 0.89 | HDAC2 (0.53) | RARBMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252252-A | Longitudinal polarization | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-10-12 | — | — | US | disclosed |
| US-5120467-A | Longitudinal polarization and-or cross-polarization | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-06-09 | — | — | US | disclosed |
| US-4723005-A | CONTAINING POLARIZED CYANO OR HALOGEN SUBSTITUENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-02-02 | — | — | US | disclosed |
| EP-0139996-A1 | Anisotropic compounds and liquid crystal mixtures | MERCK PATENT GmbH (DE) | 1985-05-08 | — | — | EP | disclosed |