Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12356795 | 0.95 | LMNA (0.67) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL30988239 | 0.86 | LMNA (0.58) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL24920664 | 0.82 | LMNA (0.65) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL17072362 | 0.82 | LMNA (0.54) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL10041856 | 0.82 | LMNA (0.54) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL16882932 | 0.81 | ESR1 (0.67) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL1257898 | 0.81 | ESR1 (0.83) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL23506629 | 0.81 | ESR1 (0.83) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL1257273 | 0.81 | ESR1 (0.83) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| Phenol SCHEMBL29040626 | 0.81 | ESR1 (0.83) | LMNAESR1ESR2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5221911-A | — | — | None | — | — | JP | disclosed |
| JP-H05221911-A | PHENOLIC COMPOUND | MITSUI TOATSU CHEM INC | 1993-08-31 | — | — | JP | disclosed |