Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 15/20 | 0.50 |
| ▸ | PPARA | Q07869 | 13/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509970 | 0.86 | KLK7 (0.48) | SRRKLK7PPARGPPARA | |
| SCHEMBL22767674 | 0.84 | PPARG (0.55) | ACEKLK7PPARGPPARA | |
| SCHEMBL359777 | 0.84 | PPARG (0.51) | SRRACEKLK7PPARGPPARA | |
| SCHEMBL359778 | 0.84 | PPARG (0.51) | SRRACEKLK7PPARGPPARA | |
| SCHEMBL360652 | 0.81 | KLK7 (0.68) | KLK7 | |
| SCHEMBL360653 | 0.81 | KLK7 (0.68) | KLK7 | |
| SCHEMBL28278431 | 0.81 | SRR (0.59) | SRRACEPPARGPPARA | |
| SCHEMBL352986 | 0.81 | SRR (0.59) | SRRACEPPARGPPARA | |
| SCHEMBL10407749 | 0.81 | SRR (0.59) | SRRACEPPARGPPARA | |
| SCHEMBL359759 | 0.79 | KLK7 (0.57) | KLK7PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |