Sugi Predict

Sugi Predict / Compounds / SCHEMBL9554386

SCHEMBL9554386

SCHEMBL9554386

CCCc1c(C(F)F)n(C(=O)CC2CCCCC2)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ AGTR1 P30556 6/20 0.43
▸ AGTR2 P50052 6/20 0.43
▸ PPARG P37231 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9554055 0.96 AGTR1 (0.46) AGTR1AGTR2PPARG
SCHEMBL9554126 0.94 AGTR1 (0.39) AGTR1AGTR2PPARG
SCHEMBL9554741 0.91 AGTR1 (0.40) AGTR1AGTR2PPARG
SCHEMBL9532576 0.90 AGTR1 (0.43) AGTR1AGTR2PPARG
SCHEMBL9553587 0.90 AGTR1 (0.42) AGTR1AGTR2PPARG
SCHEMBL9530997 0.90 AGTR1 (0.41) AGTR1AGTR2PPARG
SCHEMBL9553833 0.89 AGTR1 (0.43) AGTR1AGTR2PPARG
SCHEMBL9554250 0.89 AGTR1 (0.43) AGTR1AGTR2PPARG
SCHEMBL9534210 0.89 AGTR1 (0.38) AGTR1AGTR2
SCHEMBL9554222 0.89 AGTR1 (0.39) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5238952-A Treating glaucoma disorders G. D. SEARLE & CO. (US) 1993-08-24 — — US disclosed
WO-1992007834-A1 N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1992-05-14 — — WO disclosed
US-5087634-A N-substituted imidazol-2-one compounds for treatment of circulatory disorders G. D. SEARLE & CO. (US) 1992-02-11 — — US disclosed