SCHEMBL9554390

SCHEMBL9554390

CCCc1c(C(=O)O)n(-c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 9/20 0.46
AGTR2 P50052 8/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9533862 0.95 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL9554071 0.91 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL9035531 0.90 AGTR1 (0.48) AGTR1AGTR2
SCHEMBL9554361 0.89 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL9554116 0.89 AGTR1 (0.44) AGTR1AGTR2
SCHEMBL9035486 0.89 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL9532158 0.88 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL9554148 0.88 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL9531421 0.87 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL9035914 0.87 AGTR1 (0.46) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5238952-A Treating glaucoma disorders G. D. SEARLE & CO. (US) 1993-08-24 US disclosed
US-5087634-A N-substituted imidazol-2-one compounds for treatment of circulatory disorders G. D. SEARLE & CO. (US) 1992-02-11 US disclosed