Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.43 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554577 | 1.00 | AGTR1 (0.43) | AGTR1AGTR2CECR2 | |
| SCHEMBL9554283 | 0.93 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9530953 | 0.93 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9530957 | 0.93 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9554281 | 0.93 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9536001 | 0.91 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9535998 | 0.91 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9553748 | 0.90 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9553746 | 0.90 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9532494 | 0.90 | AGTR1 (0.57) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238952-A | Treating glaucoma disorders | G. D. SEARLE & CO. (US) | 1993-08-24 | — | — | US | disclosed |
| WO-1992007834-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |
| US-5087634-A | N-substituted imidazol-2-one compounds for treatment of circulatory disorders | G. D. SEARLE & CO. (US) | 1992-02-11 | — | — | US | disclosed |