Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554586 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 | |
| SCHEMBL7300860 | 0.85 | SLC13A5 (0.56) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 | |
| SCHEMBL419615 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 | |
| SCHEMBL10941763 | 0.83 | SLC13A5 (0.54) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 | |
| SCHEMBL559624 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 | |
| SCHEMBL27639696 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 | |
| SCHEMBL3730337 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 | |
| SCHEMBL9557132 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 | |
| SCHEMBL10029379 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 | |
| SCHEMBL10029155 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |